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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS7
All Species:
26.97
Human Site:
S421
Identified Species:
49.44
UniProt:
O14512
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14512
NP_055413.1
581
62969
S421
L
K
G
K
P
D
G
S
F
L
V
R
D
S
S
Chimpanzee
Pan troglodytes
XP_512211
535
59559
V361
V
A
R
V
Y
D
S
V
Q
S
S
G
P
M
V
Rhesus Macaque
Macaca mulatta
XP_001082440
360
39867
E215
P
M
N
W
E
D
A
E
M
K
L
K
G
K
P
Dog
Lupus familis
XP_548159
411
45633
S265
S
D
P
R
Y
I
L
S
L
S
F
R
S
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHQ2
579
62765
S419
L
K
G
K
P
D
G
S
F
L
V
R
D
S
S
Rat
Rattus norvegicus
XP_001081372
564
60962
S404
L
K
G
K
P
D
G
S
F
L
V
R
D
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506079
518
56852
E357
M
V
V
T
S
L
T
E
E
L
K
K
L
A
R
Chicken
Gallus gallus
XP_423895
264
29931
K119
A
S
L
R
E
L
E
K
C
G
W
Y
W
G
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684929
733
79803
S573
L
R
G
K
P
D
G
S
F
L
V
R
D
S
S
Tiger Blowfish
Takifugu rubipres
NP_001116335
565
61771
S405
L
K
G
K
P
D
G
S
F
L
V
R
D
S
S
Fruit Fly
Dros. melanogaster
NP_523390
1016
110741
S866
L
S
S
E
P
D
G
S
F
I
V
R
D
S
S
Honey Bee
Apis mellifera
XP_397211
804
90105
S641
L
S
N
E
P
D
G
S
F
I
V
R
D
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792866
847
94386
A442
P
R
S
V
S
E
G
A
A
I
L
A
S
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
43
69.5
N.A.
97.4
95.1
N.A.
24.1
42.6
N.A.
38.2
52.3
22
24.8
N.A.
27.8
Protein Similarity:
100
36.8
49.5
69.7
N.A.
98.1
95.8
N.A.
34.4
43.7
N.A.
48.2
62.4
32.1
39.2
N.A.
39
P-Site Identity:
100
6.6
6.6
13.3
N.A.
100
100
N.A.
6.6
0
N.A.
93.3
100
73.3
73.3
N.A.
6.6
P-Site Similarity:
100
13.3
20
20
N.A.
100
100
N.A.
26.6
6.6
N.A.
100
100
86.6
86.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
8
8
8
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
70
0
0
0
0
0
0
54
0
0
% D
% Glu:
0
0
0
16
16
8
8
16
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
54
0
8
0
0
0
0
% F
% Gly:
0
0
39
0
0
0
62
0
0
8
0
8
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
24
0
0
0
0
0
% I
% Lys:
0
31
0
39
0
0
0
8
0
8
8
16
0
8
0
% K
% Leu:
54
0
8
0
0
16
8
0
8
47
16
0
8
0
0
% L
% Met:
8
8
0
0
0
0
0
0
8
0
0
0
0
8
0
% M
% Asn:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
16
0
8
0
54
0
0
0
0
0
0
0
8
0
16
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% Q
% Arg:
0
16
8
16
0
0
0
0
0
0
0
62
0
0
16
% R
% Ser:
8
24
16
0
16
0
8
62
0
16
8
0
16
54
54
% S
% Thr:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
8
8
8
16
0
0
0
8
0
0
54
0
0
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
8
0
8
0
0
% W
% Tyr:
0
0
0
0
16
0
0
0
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _